Lip lines — sometimes called 'smoker's lines' even if you've never smoked — are definitely treated with botox, yes. The technique is a bit more delicate than forehead treatment because the muscles around the mouth are involved in so many expressions and functions like talking and eating. A skilled injector will use a very light touch and small amounts in that area to avoid affecting normal movement. It's considered a more advanced zone, so it's especially important to go to someone experienced with perioral injections.